Research to Improve the Care of Persons at Clinical High Risk for Psychotic Disorders (R34) Grant

Funding Opportunity Number: RFA-MH-14-212

Given the highly disruptive and disabling nature of psychotic disorders, early intervention has been recommended as a means of preventing psychosis onset among at-risk individuals, as well as averting other adverse outcomes such as mood syndromes, substance abuse disorders, and functional decline in social, academic, and vocational domains. This funding opportunity announcement, along with the companion announcements, aims to support research that will inform a step-wise approach to early psychosis intervention in the United States. The goals of this initiative are to encourage applications that (1) propose intervention development and pilot feasibility studies of strategies to target symptomatic and functional difficulties associated with clinical risk states for psychosis; (2) explore mediators/mechanisms of action of these interventions; (3) contribute to an evidence base to inform stepped-care models of early psychosis intervention; and (4) determine the feasibility for implementing such approaches in community-based treatment settings. To view the grant’s full description click here.

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